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Will COVID-19 Test Kit Be Effective if Coronavirus Mutate?

Date:Dec 25, 2020

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The new variant of coronavirus found in UK has raised alarm around the whole world. It has also been confirmed in other countries like Belgium, Denmark and Australia. It’s reported that the variant may be up to 70% more transmissible and may spread more quickly. However, there is no evidence that this variant could cause a higher mortality rate.

What worries the public is that will COVID-19 test kit be effective if Coronavirus mutate.

It’s true that viruses mutate all the time, including the coronavirus. The new strain of COVID-19 has accumulated 17 new mutations and 8 of the 17 mutations are on the spike protein as most of the COVID-19 Test Kits on the market are developed targeting the S protein.    Nevertheless, it should be noted that the majority of mutations would have very small effect on the virus. Also, most test kits are designed for multiple targets on the gene sequence, and the variants will not affect this kind of test kits. Only the reagent selects the single target on the gene sequence is likely to be affected with a lower accuracy.

The Principle of Singclean’s Antigen Test Kit

The development of Singclean’s antigen test kit is based on the public information after the analysis of the COVID-19 gene sequence and expresses antigen from the N, S, E, and M protein gene sequences of the COVID-19 with gene immunization. So, Singclean's detection target is the protein shell corresponding to the N, S, E, and M proteins of the COVID-19. And the mutations of COVID-19 would not affect the antigen test kit apparently.

The Market Trend of COVID-19 Test Kits

Countries have been using rapid antigen tests for mass screening and tracking to contain the worsening COVID-19 situation.    According to Grand View Research, the global COVID-19 test kits market size was estimated at USD 3.28 billion in 2020 and would see a compound annual growth rate of 5% to reach USD 4.63 billion by 2027.    There are still many uncertainties of COVID-19, but we know the vaccination experts, healthcare workers, the authorities and we, the normal people are doing everything we can to help end this pandemic.


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